Studies of Thrombolytic, Antioxidant and Cytotoxic Properties of Two Asteraceous Plants of Bangladesh

نویسندگان

  • Md. Hassan Kawsar
  • Md. Al Amin Sikder
  • Md. Sohel Rana
  • Ishrat Nimmi
  • Mohammad A. Rashid
چکیده

Two Bangladeshi medicinal plants Tridax procumbens and Vernonia cinerea have been investigated for their in vitro thrombolytic, membrane stabilizing and cytotoxic properties. The total phenolic content was also determined and expressed in gallic acid equivalent. Among the two plants, the methanol extract of T. procumbens exhibited highest thrombolytic activity with clot lysis value of 21.15%. Standard streptokinase and water were used as positive and negative control which demonstrated 66.77% and 2.64% lysis of clot of human blood. The membrane stabilizing activity was assessed by using hypotonic solution and heat-induced methods and was compared with acetyl salicylic acid as standard drug.

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تاریخ انتشار 2012